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目的：观察妊娠期补充维D钙咀嚼片或葡萄糖酸钙口服液的临床效果。方法将160例妊娠20周妇女随机分成两组，观察组80例，口服维D钙咀嚼片，对照组80例，口服葡萄糖酸钙口服液，两组孕妇补钙前查血钙，补钙后分别于孕28、36周复查血钙，并定期产前检查。结果观察组孕28周、孕36周血钙分别为2.45±0.11、2.33±0.17（mmol/L），对照组孕28周、孕36周血钙分别为2.13±0.12、2.08±0.12（mmol/L），观察组血钙较对照组明显升高，两组比较差异有统计学意义（X2分别为4.479、3.151，均P<0.05），观察组的临床缺钙症状明显低于对照组，且妊娠期高血压疾病、胎儿生长受限、产后出血、副反应发生率均明显低于对照组，两组比较差异有统计学意义（X2分别为138.53、134.79、452.82、137.19、208.47，均P<0.05）。结论孕期补充维D钙咀嚼片可明显改善缺钙症状、降低妊娠期高血压疾病、胎儿生长受限及产后出血发生率。“,”Objective To 0bserve the clinical efficacy of supplementation Victoria D Calcium Chewable Tablets or calcium gluconate oral solution during pregnancy. Methods 160 cases of women 20 weeks of pregnancy were randomly divided into two groups, 80 cases in the observation group, oral Victoria D Calcium Chewable Tablets, 80 cases in the control group, oral calcium gluconate oral solution, check calcium of the two groups of pregnant women before the investigation, review calciumat 28, 36 weeks after pregnancy calcium and regular prenatal care. Result Observer Group 28 weeks pregnant, 36 weeks pregnant calcium were 2.45± 0.11,2.33± 0.17 (mmol/L), the control group 28 weeks pregnant, 36 weeks pregnant calcium were 2.13 ± 0.12, 2.08 ± 0.12 (mmol/L). The observation group calcium was significantly higher than in the control group, the difference was statistically significant (x2 respectively 4.479、3.151, all P <0.05), the clinical symptoms of calcium deficiency in the observation group was significantly lower than the control group, and hypertensive disorders in pregnancy, fetal growth restriction, The incidence of postpartum hemorrhage was significantly lower than the control group, the difference was statistically significant (x2respectively138.53、134.79、452.82、137.19、208.47, all P<0.05).Conclusion Victoria D Calcium Chewable Tablets supplementation during pregnancy may reduce the incidence of calcium deficiency symptoms and reduce hypertensive disorders in pregnancy, fetal growth restriction and incidence of postpartum hemorrhage, very beneficial for the mother and child .