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目的探讨宫颈环形电切术(LEEP)对宫颈上皮内瘤变(CIN)患者术后妊娠及分娩结局的影响。方法 80例CIN患者作为观察组(采用LEEP治疗),50例同期在门诊就诊的无宫颈手术且曾患宫颈炎的患者作为对照组。记录观察组患者宫颈长度、宫颈管和宫颈内口宽度在术后的变化,对比两组的妊娠结局和围生儿情况。结果与术前比较,术后观察组患者宫颈长度明显缩短,宫颈管宽度明显增宽(P<0.05)。观察组围生儿中,早产率、早产胎膜早破率明显高于对照组,新生儿体重明显低于对照组(P<0.05)。结论对宫颈病变的育龄妇女,应明确LEEP手术指征,尽可能多的保留正常宫颈组织,预防宫颈机能不全和降低不良妊娠结局的发生风险。
Objective To investigate the effect of cervical ring electrosurgical excision (LEEP) on postoperative pregnancy and delivery outcomes in patients with cervical intraepithelial neoplasia (CIN). Methods Eighty patients with CIN were selected as the observation group (treated with LEEP) and 50 patients without cervical cancer who had been treated in the outpatient department during the same period and had cervicitis as the control group. The changes of cervical length, the width of cervical canal and cervical internal ostium in the observation group were recorded, and the pregnancy outcome and perinatal condition were compared between the two groups. Results Compared with preoperative, the length of cervical canal in patients in observation group was significantly shortened and the width of cervical canal widened significantly (P <0.05). Perinatal infants in the observation group, premature birth rate, premature rupture of membranes was significantly higher than the control group, newborn weight was significantly lower than the control group (P <0.05). Conclusions For women of childbearing age with cervical lesions, the indications of LEEP operation should be clear, as much as possible to retain normal cervical tissue, prevent cervical insufficiency and reduce the risk of adverse pregnancy outcomes.