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浙江大学肿瘤研究所和免疫研究所历时５年完成的一项研究显示 ,用转基因手段可扩大单抗导向超抗原融合蛋白治疗肿瘤范围 ,联合应用白细胞介素１８和趋化因子可进一步增强其抗肿瘤作用。课题组用转基因手段将编码为Ｃ２１５的肿瘤抗原转染到不表达该抗原的小鼠黑色素瘤Ｂ１６细
A study completed five years after the Institute of Oncology and Immunology of Zhejiang University showed that the use of genetically modified monoclonal antibody-guided superantigen fusion proteins to treat tumors, combined with the use of interleukin-18 and chemokines can further enhance its resistance. Tumor effect. The research group transfected the tumor antigen coded as C215 to the mouse melanoma B16 that did not express the antigen by means of transgenic methods.