虽然很难作出定量说明,但药物不良反应是现代治疗无法回避的后果似无何疑义。任何药物都包含着潜在的危害,因此决定开始药物治疗,都要认真权衡利弊,以定取舍。病人大多都需用多种药物,这样不但会使药物不良反应的发生机率增高,还会增加药物相互作用的机会。由于伴有内在疾病的影响,所用药物又不只一种,因此要确定不良反应是由哪一种药物引起的,常非易事。有关药物不良反应发生率的研究,主要来自教学医院的医疗部门。波士顿药物监护协作计划的统计表明:药物不良反应的发生率为5％,大多是轻微和自限性的。其它研究估计的发生率还要高些,特别是在危重病人中。近来对病房合并症的一份研 Although it is difficult to quantify this, there is no doubt that adverse drug reactions are an unavoidable consequence of modern treatment. Any drug contains potential hazards, so the decision to start drug treatment, we must carefully weigh the pros and cons, to decide. Most patients need to use a variety of drugs, which will not only increase the incidence of adverse drug reactions, but also increase the chance of drug interactions. Due to the inherent disease associated with the use of more than one drug, so to determine which side effects caused by the drug is often not easy. The incidence of adverse drug reactions research, mainly from the teaching hospital medical department. Statistics from the Boston Drug Care Coordination Program show that the incidence of adverse drug reactions is 5%, mostly mild and self-limiting. Other studies estimate the incidence is even higher, especially in critically ill patients. A recent study of ward complications