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目的观察曲美他嗪治疗急性心肌梗死后心律失常的临床疗效及安全性。方法将80例急性心肌梗死后心律失常患者随机分为二组,对照组应用常规治疗,治疗组在对照组的基础上加用盐酸曲美他嗪治疗。观察二组用药前后心律失常发作情况、药物的耐受性及不良反应。结果治疗组与对照组均能减少心律失常发作,但治疗组总有效率为90.0%,高于对照组(70.0%),差异有统计学意义(P<0.05)。结论盐酸曲美他嗪可有效治疗急性心肌梗死后心律失常发作,值得临床推广应用。
Objective To observe the clinical efficacy and safety of trimetazidine in the treatment of arrhythmia after acute myocardial infarction. Methods Eighty patients with acute arrhythmia after acute myocardial infarction were randomly divided into two groups. The control group was treated with conventional therapy. The treatment group was treated with trimetazidine hydrochloride on the basis of the control group. Observed two groups before and after treatment of arrhythmia attack, drug resistance and adverse reactions. Results Both the treatment group and the control group could reduce the incidence of arrhythmia. However, the total effective rate was 90.0% in the treatment group, which was higher than that in the control group (70.0%). The difference was statistically significant (P <0.05). Conclusion Trimetazidine hydrochloride can effectively treat the arrhythmia after acute myocardial infarction, which is worthy of clinical application.