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以往对结素皮内试验反应的判断只观察对某种浓度的结素有无反应(阴性或阳性)。近年来已注意到反应的大小与反应大小的频率分布的量的变化。Palmer等氏在人群与动物进行了许多系统观察,发现在世界不同的地区对5个单位结素皮内试验反应有很大不同,在有些地区结素试验的反应明显的分成两部——大反应者与小反应者,人群因而可以分成两类即结核感染者与未感染者。但在许多其他地区大部分反应是中等度大小的,区分两类很困难。目前对造成复杂的中等度反应正进行着研
In the past, the determination of the intradermal skin test reaction only observed whether there was any reaction (negative or positive) to a certain concentration of nodules. In recent years, attention has been paid to the variation of the frequency distribution of reaction size and reaction size. Palmer et al. Conducted many systematic reviews of populations and animals and found that there are significant differences in the 5-unit intradermal test responses in different parts of the world. In some areas, the response of the nodule test is clearly divided into two large Responders and small responders, the population can thus be divided into two categories, namely infected and non-infected tuberculosis. However, in most of the other regions, the majority of responses are of moderate size, and distinguishing between the two is difficult. There is currently ongoing research into the complex middle-level response