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目的分析中老年人体质指数与肝功能及血脂之间的关系。方法采用整群抽样的方法,抽取广州市海珠区江海街社区50岁以上中老年人共823人进行问卷调查、体格检查和实验室检查,获得研究对象基本资料、身高、体重、丙氨酸氨基转移酶(ALT)、总胆固醇(TC)及甘油三酯(TG)等指标值,计算体质指数(BMI)并进行体重分组,对各组肝功能、血脂水平进行比较和相关性分析。结果方差分析不同体重组TC均数比较,差别无统计学意义(F=0.177,P=0.910),TG均数差异有统计学意义(F=7.10,P=0.000),不同体重组ALT差别有统计学意义,(F=792,P=0.000);Pearson相关分析50岁以上中老人ALT值分别与BMI和TG之间皆存在正相关性(相关系数r分别为0.187,0.158,P值分别为0.008,0.000),并且不认为ALT与TC之间存在相关性(P>0.05)。结论控制体重一定程度上能控制高甘油三酯型高脂血症,对保护肝功能亦有积极意义。
Objective To analyze the relationship between body constitution index and liver function and blood lipid in middle-aged and elderly people. Methods A total of 823 middle-aged and elderly people aged over 50 in Jianghai Street community in Haizhu District of Guangzhou City were enrolled in this study. Questionnaires, physical examination and laboratory tests were conducted to obtain the basic information of the study subjects such as height, weight, (ALT), total cholesterol (TC), and triglyceride (TG) were calculated. Body mass index (BMI) was calculated and divided into groups according to body weight. Liver function and blood lipid levels in each group were compared and analyzed. RESULTS ANOVA Analysis There was no significant difference in mean of TC between groups with different body weight (F = 0.177, P = 0.910). There was significant difference between the two groups (F = 7.10, P = 0.000) (F = 792, P = 0.000). Pearson correlation analysis showed that there was a positive correlation between ALT value of middle-aged and elderly people over 50 years old and BMI and TG (r = 0.187,0.158, P = 0.008, 0.000), and there was no correlation between ALT and TC (P> 0.05). Conclusion To some extent, weight control can control hypertriglyceridemia, which is also of positive significance for the protection of liver function.