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目的分析和探讨慢性乙型肝炎与肝硬化患者感染SEN病毒的危险因素及采取的护理措施。方法选取医院2011年3月-2013年6月收治的慢性乙型肝炎与肝硬化患者为研究对象,使用SEN-V PCR引物探讨SEN病毒和慢性肝炎的关系,比较在病毒感染因素的作用下患者感染SEN病毒的概率;采用SPSS12.0软件进行统计分析。结果 SEN病毒主要有输血传播、静脉吸毒、母婴垂直传播以及性传播等传播途径,临床上常表现为SEN病毒单独感染和HBV等病毒合并感染;接受输血、有吸毒史、经母婴传播和性病慢性乙型肝炎与肝硬化患者的感染率分别为31.58%、36.84%、40.00%、34.38%,而未接受输血、无吸毒史、未经母婴传播和非性病患者的感染率为3.53%、3.73%、4.24%、5.41%,各组间比较差异均有统计学意义(P<0.01)。结论输血治疗和接触血制品、静脉吸毒、母婴以及性交等途径是慢性乙型肝炎与肝硬化患者感染SEN病毒的主要危险因素,患者应加强预防和防范,采取必要的安全护理措施,降低感染SEN病毒的概率。
Objective To analyze and explore the risk factors of SEN virus infection in patients with chronic hepatitis B and cirrhosis and the nursing measures taken. Methods The patients with chronic hepatitis B and cirrhosis admitted from March 2011 to June 2013 in our hospital were enrolled in this study. The relationship between SEN virus and chronic hepatitis was explored by using SEN-V PCR primers. Compared with patients with viral hepatitis SEN virus infection probability; using SPSS12.0 software for statistical analysis. Results The main pathogens of SEN were blood transfusion, intravenous drug use, vertical transmission of mother and infant and sexually transmitted diseases. Clinical manifestations include SEN virus infection alone and HBV infection. Transfusion, drug abuse history, mother-to-child transmission and The infection rate of STD patients with chronic hepatitis B and cirrhosis was 31.58%, 36.84%, 40.00% and 34.38% respectively. The infection rate without blood transfusion, no drug abuse history, without mother-to-child transmission and non-STD was 3.53% , 3.73%, 4.24% and 5.41% respectively. There was significant difference among the groups (P <0.01). Conclusion Transfusion therapy and contact with blood products, intravenous drug use, maternal and infant and sexual intercourse are the main risk factors of SEN virus infection in patients with chronic hepatitis B and cirrhosis. Patients should be more preventive and preventive measures, take necessary safety nursing measures to reduce infection SEN virus probability.