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目的探讨良性前列腺增生症(benign prostatic hyperplasia,BPH)与代谢综合征(metabolic syndrome,MS)的相关性。方法选择2010年5月在四川大学华西医院体检中心体检的老年男性共666例,进行MS及BPH相关指标的检查,分析比较BPH综合定义、下尿路症状、前列腺体积与MS及其组分(CDS2007标准)的相关性。结果高血压与BPH诊断有明显相关性[OR=1.309,95%CI(1.033,1.661)],低HDL-C血症(HDL-C<1.04 mmol/L)是IPSS评分异常的危险因素[OR=1.573,95%CI(1.330,1.997)],前列腺体积与肥胖、高血压、低HDL-C血症及MS呈正相关(P均<0.05)。结论 MS及其组分对BPH的影响主要体现在前列腺体积的变化,而对下尿路症状的影响相对较小。
Objective To investigate the relationship between benign prostatic hyperplasia (BPH) and metabolic syndrome (MS). Methods A total of 666 elderly men who were examined at Huaxi Hospital of Sichuan University in May 2010 were selected for MS and BPH related indexes examination. The comprehensive definition of BPH, lower urinary tract symptoms, prostate volume and MS and its components CDS2007 standard) relevance. Results Hypertension was significantly associated with the diagnosis of BPH [OR = 1.309, 95% CI (1.033, 1.661)] and low HDL-C (HDL-C <1.04 mmol / L) = 1.573, 95% CI (1.330, 1.997)]. Prostate volume was positively correlated with obesity, hypertension, low HDL-C and MS (all P <0.05). Conclusion The effects of MS and its constituents on BPH are mainly reflected in the changes of the volume of the prostate, while the effects on the lower urinary tract symptoms are relatively small.