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近年来,表鬼臼噻吩甙(Teniposide,Vumon,VM_(26))在恶性脑胶质瘤的化疗中获得了一定效果,已引起普遍关注。本文介绍VM_(26)治疗1例脊髓圆锥马尾恶性室管膜瘤术后椎管外多发性转移远期观察的经验,供临床参考。 资料 患者 男,35岁,于1983年11月15日入院。入院前1个月腰痛起病,10天后出现尿潴留、便秘,继以双下肢放射痛伴进行性无力,并迅速导致截瘫。经当地留置导尿管后转来我院。入院时体检:双下肢完全性松弛性截瘫,腰_5以下痛觉减退,骶_1以下痛觉消失,双下肢膝、跟反射消失,位置觉消失,肛门反射消失,未引出病理反射。腰椎穿刺脑脊液蛋白细胞分离现象:蛋白700mg％,细胞数正常。压颈试验不
In recent years, teniposide (Vipon, VM_ (26)) has obtained some effects in the chemotherapy of malignant glioma and has attracted widespread attention. This article describes the VM_ (26) treatment of a case of spinal conical pituitary hysteroscopic malignant ependymoma long-term observation of multiple postoperative transitional canal for clinical reference. Male patient, 35 years old, was admitted to hospital on November 15, 1983. 1 month before admission, low back pain onset, urinary retention after 10 days, constipation, followed by lower extremity radiating pain with progressive weakness and quickly lead to paraplegia. After the local indwelling catheter transferred to our hospital. Physical examination on admission: complete paralysis of lower extremities, pain relief below waist 5, loss of sensation below sacral level 1, disappearance of lower extremity knees, disappearance of reflex, loss of position sensation, disappearance of anus reflex, absence of pathological reflex. Lumbar puncture cerebrospinal fluid protein cells isolated: protein 700mg%, normal cell number. Pressure neck test is not