The galvanic-coupled intrabody communication (GCIBC) uses the human body as the channel for data transmission. The signal flow through different paths within different measure-ment schemes, resulting in distinct deviations in the experimental results. This method completely uses human body channel to transmit low-power signals, and has good anti-interference perform-ance. However, for a long time, the channel research of GCIBC has not determined a set of recog-nized and accurate measurement methods and standards. However, few researcher analyze the dif-ferences and principles between different measurement methods. This paper aims at three com-monly used measurement methods. Abstract the equivalent schematic diagrams of three measure-ment schemes: direct measurement, using high-precision differential probe and using balun. The sig-nal return paths generated by three measurement methods are analyzed, the impedance matching and energy transmission efficiency are compared. According to the analysis, the empirical expres-sions in different cases are listed. The mechanism between the channel measurement results gener-ated by the set experimental configuration and the comparison experiment is clarified. The compar-ison experiment with complete floating measurement is carried out as a reference to verify the pro-posed opinion. The measurement error caused by different experimental configurations is verified. This study can provide a reference opinions for the experimental error analysis of GCIBC research in the future, and provide suggestions for the selection of experimental configuration.