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目的:对扁平疣采用甘露聚糖肽进行治疗的临床效果进行观察、分析。方法:选取自2011年3月到2013年8月在我院接受扁平疣治疗的105例患者,通过随机抽样的方法分为对照组与观察组,其中对照组43例,给予他扎罗汀乳膏联合重组人干扰素α-2b凝胶外用;观察组62例,在采用对照组患者治疗方法的基础上,再肌肉注射5mg甘露聚糖肽药液,频率为两日一次。7周以后对治疗效果进行观察。结果:观察组患者痊愈者17例,显效者20例,好转者17例,无效者8例,总体有效率达87.1%;对照组患者痊愈者8例,显效者12例,好转者11例,无效者12例,总体有效率达72.1%。两组患者比较差异存在统计学意义(P<0.05)。结论:采用甘露聚糖肽进行治疗的观察组的临床疗效要明显优于单纯使用外用药物进行治疗的对照组,因此扁平疣采用甘露聚糖肽治疗值得在临床中广为推广。
Objective: To observe and analyze the clinical effect of treatment of flat warts with mannan peptide. Methods: From March 2011 to August 2013, 105 patients who received flat wart treatment in our hospital were divided into control group and observation group by random sampling method. The control group received 43 cases of tazarotene Cream combined with recombinant human interferon α-2b gel for external use; observation group of 62 cases, using the control group of patients based on the treatment method, and then intramuscular injection of 5mg mannan peptide solution at a frequency of once every two days. After 7 weeks the treatment effect was observed. Results: In the observation group, 17 cases were cured, 20 cases were markedly improved, 17 cases were improved, 8 cases were ineffective, and the overall effective rate was 87.1%. In the control group, 8 cases were cured, 12 cases were markedly improved, 11 cases were improved, Invalid in 12 cases, the overall effective rate of 72.1%. The difference between the two groups was statistically significant (P <0.05). Conclusion: The clinical efficacy of the observation group treated with mannan peptide is better than that of the control group treated with topical drugs alone. Therefore, the treatment of flat warts with mannan peptide deserves wide application in clinic.