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目的观察复方丹参注射液联合硫酸镁治疗轻度子痫前期对妊娠结局及母婴预后的影响。方法将212例子痫前期患者随机分为试验组和对照组各106例。试验组给予复方丹参注射液联合硫酸镁治疗,对照组仅给予硫酸镁治疗。观察和比较2组患者妊娠和母婴预后结局。结果试验组总有效率为94.34%高于对照组的78.30%,差异有统计学意义(P<0.05)。试验组自然分娩率高于对照组,妊娠终止、剖宫产等不良妊娠结局和产后出血、宫缩乏力、胎儿窘迫、新生儿窒息等不良母婴预后结局发生率均低于对照组,差异均有统计学意义(P<0.05)。结论复方丹参注射液联合硫酸镁治疗轻度子痫前期可显著改善患者妊娠和母婴结局。
Objective To observe the effect of Fufang Danshen injection and magnesium sulfate on pregnancy outcome and maternal and infant prognosis in mild preeclampsia. Methods 212 preeclampsia patients were randomly divided into experimental group and control group of 106 cases. The experimental group was given compound Danshen injection combined with magnesium sulfate, while the control group only given magnesium sulfate. The pregnancy and maternal and infant prognosis were observed and compared in two groups. Results The total effective rate of the experimental group was 94.34% higher than that of the control group (78.30%), the difference was statistically significant (P <0.05). The rate of natural childbirth in the experimental group was higher than that of the control group. The incidence of adverse maternal and infant outcomes such as adverse pregnancy outcome such as cesarean section, postpartum hemorrhage, uterine atony, fetal distress and neonatal asphyxia were lower than those in the control group There was statistical significance (P <0.05). Conclusion Compound Danshen injection combined with magnesium sulfate in mild preeclampsia can significantly improve the outcome of pregnancy and maternal and infant.