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浆细胞病系指浆细胞或产生免疫球蛋白的B淋巴细胞过度增殖引起的一组疾病,包括髓外浆细胞瘤(EMP)、骨的孤立性浆细胞瘤和多发性骨髓瘤(MM)[1]。其中EMP是原发于骨髓造血组织以外的浆细胞增殖性肿瘤,其确切的发病机制并不清楚,较为罕见,约占所有浆细胞肿瘤的3%~4%,男性发病率高于女性[2]。本文结合本院1例头顶部EMP并进行文献复习,对EMP的诊断及病理特征进行分析,旨在提高诊断水平,避免漏诊和误诊。
Plasma cell disease refers to a group of diseases caused by hyperproliferation of plasma cells or immunoglobulin-producing B lymphocytes, including extramedullary plasmacytoma (EMP), solitary plasmacytoma of the bone and multiple myeloma (MM) [ 1]. Among them, EMP is a plasma cell proliferative tumor other than bone marrow hematopoietic tissue. The exact pathogenesis of EMP is not clear and relatively rare, accounting for 3% ~ 4% of all plasma cell tumors. The incidence of males is higher than that of females ]. In this paper, one case of our hospital head EMP and literature review, EMP diagnosis and pathological features were analyzed to improve the diagnostic level, to avoid misdiagnosis and missed.