2. 您的位置
3. 首页
4. 期刊论文
5. Celastrol as a tool for the study of the biological events of metabolic diseases

Celastrol as a tool for the study of the biological events of metabolic diseases

来源 :中国科学:化学英文版 | 被引量 : 0次 | 上传用户：jushicahgn

【摘 要】

：

Celastrol is a pentacyclic triterpenoid isolated from Tripterygium wilfordii that has long been used in traditional Chinese medicine for treating rheumatoid art

【作 者】

：

Gongcai Lan Jie Zhang Wenbo Ye 

【机 构】

：

GuangdongPharmaceuticalUniversity,ShanghaiKeyLaboratoryofNewDrugDesign,StateKeyLaboratoryofBioorgani

【出 处】

：

中国科学:化学英文版

【发表日期】

：

2019年4期

【关键词】

：

CELASTROL OBESITY type 2 DIABETES endoplasmic reticulum STRESS INFLAMMATION 

【基金项目】

：

Professor of Chang Jiang Scholars Program,the National Natural Science Foundation of China(81520108030,21472238,81502956,21572064,21525209,21621002,21772225,21761142003),Chinese Academy of Sciences(St

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Celastrol is a pentacyclic triterpenoid isolated from Tripterygium wilfordii that has long been used in traditional Chinese medicine for treating rheumatoid arthritis.Previous studies showed that celastrol possessed diverse biological activities,including

其他文献

Multi-functional supramolecular polymer produced from natural small molecules in a facile route

Polymeric materials are important substrates for the realization of different functions.Despite the rapid progress, there are still two big challenges in this f

期刊

POLYMERICFUNCTIONSMILDROUTE

Organic field-effect optical waveguides: a new break-through all organic optoelectronics

Optical waveguide, a physical structure that guides electromagnetic waves in the optical spectrum, is the key elements of photonic devices that perform guiding,

期刊

OpticalphysicalstructureELECTROMAGNETIC

Materials and structures for the electron transport layer of efficient and stable perovskite solar c

The electron transport layer plays a vital function in extracting and transporting photogenerated electrons, modifying the interface, aligning the interfacial e

期刊

PEROVSKITEsolarcellselectrontransportlayermetalOXIDEorganicMOLECULESMU

MAF-41 with intermediate-sized molecular sieving effect for highly selective separation of styrene

Styrene(ST)is one of the most important chemicals in the world because of its widely applications in the syntheses of rubbers or thermoplastics.However,ST is ma

期刊

SEPARATIONadsorptionSELECTIVITY

The role of organic electron donors in the initiation of BHAS base-induced coupling reactions betwee

Coupling reactions between haloarenes and arenes(including heteroarenes)that are conducted without added transition metals but in the presence of KOtBu or NaOtB

期刊

ORGANICELECTRONdonorpotassiumtert-butoxideELECTRONtransferbase-promotedh

A new strategy enabling intramolecular motion to obtain advanced photothermal materials

Recently, considerable research interest has been focused on biomedical application of the photothermal materials, such as photoacoustic imaging (PAI) and photo

期刊

RecentlyPAIPTT

Unlocking multiplexing in deep tissue

In vivo fluorescence imaging in the second near-infrared (NIR-II)window (1000-1700 nm)has been emerging as a new powerful imaging technique and demonstrated tre

期刊

UnlockingMULTIPLEXINGDEEPTISSUE

Digital dendrimer: a new horizon of information-containing polymers

DNA has long been proposed as a molecular-level data storage media with large storage capacity due to its precise sequence structure and modern sequencing techn

期刊

DIGITALDENDRIMERHORIZONinformation-containing

Violation of Environmental Protection Laws Being Rectified

【正】 Pan Yue,Deputy Director of the StateEnvironmental Protection Administration(SEPA),says that by August 17th 1162 en-terprises and projects in violation of

期刊

VIOLATIONREGULATIONSDIRECTORDEPUTYSTRENGTHENED

Molecular recognition and biological application of modified β-cyclodextrins

The molecular recognition based on cyclodextrins(CDs) has become a focus of interest in modern supramolecular chemistry.CDs are known to encapsulate various ion

期刊

HOST-GUESTCHEMISTRYmolecularRECOGNITIONCYCLODEXTRINBIOLOGICALfunction