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目的探索动态血糖监测在老年2型糖尿病患者胰岛素泵强化治疗中的应用,总结方法与优势。方法对42例患者同时采用动态血糖监测系统(CGMS)和常规手指末梢血糖监测,对结果进行统计学分析,评估CGMS监测的效果。结果 CGMS血糖值与手指末梢血糖值呈显著正相关(r=0.95,P<0.05),CGMS显著提高了高血糖、低血糖检出率,CGMS检出的低血糖次数是常规指尖血糖监测的4.7倍,所监测到的低血糖情况95.8%发生在夜间(22∶00～6∶00)。结论 CGMS能够全面、详细地反映血糖波动趋势,对提高胰岛素泵强化治疗的老年2型糖尿病患者血糖监测效果具有积极意义,为临床治疗提供了重要依据。
Objective To explore the application of dynamic blood glucose monitoring in intensive insulin therapy of elderly type 2 diabetic patients and to summarize the methods and advantages. Methods Forty-two patients underwent both CGMS and routine peripheral blood glucose monitoring, and the results were statistically analyzed to assess the effect of CGMS monitoring. Results There was a significant positive correlation between CGMS blood glucose level and peripheral blood glucose (r = 0.95, P <0.05). CGMS significantly increased the incidence of hyperglycemia and hypoglycemia. The frequency of CGMS detected by CGMS was significantly higher than that of conventional fingertip 4.7 times. 95.8% of the observed hypoglycemia occurred at night (22:00 ~ 6:00). Conclusion CGMS can reflect the tendency of blood glucose fluctuation in a comprehensive and detailed way and has positive significance for improving blood glucose monitoring in elderly patients with type 2 diabetes mellitus treated with insulin pump. It provides an important basis for clinical treatment.