本文讨论了棉酚的结构及其异构化问题,以化学反应为依据,提出其可能存在三种互变异构式的假设。近年来,用核磁共振谱证明,在中性或酸性条件下棉酚以醛式与半缩醛式混合存在,而在碱性条件下则以酮式为主。红外及紫外光谱研究证明,棉酚在溶液中存在着分子内氢键;而且证明,由于两萘环相连处碳—碳键的旋转受阻而存在着光学活性(阻碍异构)。 This paper discusses the structure and isomerization of gossypol. Based on the chemical reaction, this paper proposes the hypothesis that there may be three tautomerism. In recent years, with nuclear magnetic resonance spectroscopy proved that under neutral or acidic conditions, gossypol aldehyde and hemiacetal mixed existence, while in alkaline conditions, ketones based. Infrared and UV spectroscopic studies have shown that gossypol has intramolecular hydrogen bonds in solution and that it is optically active (hindering isomerism) due to the hindered rotation of the carbon-carbon bonds at the two naphthalene rings.