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目的探讨改良米非司酮周期疗法用于治疗围绝经期功能障碍性子宫出血的临床效果。方法将我院妇科收治围绝经期功能障碍性子宫出血患者200例,以随机抽样方法将其分为对照组和观察组,对照组患者给予常规米非司酮周期治疗,观察组患者给予改良米非司酮周期治疗,比较两组患者临床治疗总有效率,治疗前后子宫超声检查指标水平、临床复发率及闭经发生率。结果观察组患者临床治疗总有效率及治疗后内膜厚度减少程度均明显高于对照组(P<0.05);同时观察组患者临床复发率和闭经发生率均优于对照组(P<0.05)。结论改良米非司酮周期疗法用于治疗围绝经期功能障碍性子宫出血患者,可有效改善阴道不规则出血,减少内膜厚度,降低复发和闭经发生风险。
Objective To investigate the clinical effect of modified mifepristone cycle therapy in the treatment of climacteric dysfunctional uterine bleeding. Methods 200 cases of metrorrhagia patients with dysfunctional uterine bleeding in menopause were randomly divided into control group and observation group. Patients in control group were given routine mifepristone treatment. Patients in observation group were given modified rice Treatment of non-ketamine cycle, the total effective rate of clinical treatment in both groups were compared, the level of uterine ultrasound examination before and after treatment, the clinical recurrence rate and the incidence of amenorrhea. Results The total effective rate of clinical treatment and the reduction of intima thickness in the observation group were significantly higher than those in the control group (P <0.05). The clinical relapse rate and the incidence of amenorrhea in the observation group were better than those in the control group (P <0.05) . Conclusion The modified mifepristone cycle therapy for the treatment of climacteric patients with dysfunctional uterine bleeding can effectively improve vaginal irregular bleeding, reduce the thickness of the intima and reduce the risk of recurrence and amenorrhea.