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目的 探讨米索前列醇、氧化亚氮用于人工流产的临床效果。方法 将行人工流产的妇女 180例随机分米索前列醇组、氧化亚氮组、米索前列醇氧化亚氮组 ,每组 6 0例。分别观察镇痛效果、宫颈扩张情况、手术时间、术中出血及不良反应。结果 镇痛效果 :氧化亚氮组、米索前列醇氧化亚氮组与单用米索前列醇组相比差异有非常显著意义 (P <0 0 1)。宫颈扩张情况 :米索前列醇组、米索前列醇氧化亚氮组与单用氧化亚氮组相比差异有非常显著意义 (P <0 0 1)。术中出血、手术时间三组相比差异无显著意义。结论 米索前列醇和氧化亚氮联合用于人工流产 ,既可实现无痛人流又可达到良好的宫颈扩张效果 ,值得推广应用。
Objective To investigate the clinical effect of misoprostol and nitrous oxide in induced abortion. Methods One hundred and eighty women with induced abortion were randomly divided into misoprostol group, nitrous oxide group and misoprostol nitrous oxide group, with 60 cases in each group. Respectively observe the analgesic effect, cervical dilatation, operation time, intraoperative bleeding and adverse reactions. Results Analgesia effect: There was significant difference between nitrous oxide group, misoprostol nitrous oxide group and misoprostol group (P <0.01). Cervical dilation: There was significant difference between misoprostol group and misoprostol nitrous oxide group and nitrous oxide group alone (P <0.01). There was no significant difference between the three groups in intraoperative bleeding and operation time. Conclusion Misoprostol and nitrous oxide combined for artificial abortion, both painless and achieve good cervical dilation effect, it is worth popularizing and applying.