血清透明质酸(Hyaluronic acid,HA),由体内各组织的间质纤维细胞合成,肝脏内皮细胞摄取分解,少量小分子由肾小球滤过,排泄。当肝、肾脏功能受损时,血清HA升高,且与病变的严重程度有关,HA是反映肝功能较敏感的指标,对早期肝硬化的诊断具有重要意义。本文应用放射免疫方法检测了67例肝病患者血清中HA水平;同时与甲胎蛋白(AFP)的水平对比分析,以判断其对肝病的诊断价值,现将结果报告如下: Hyaluronic acid (HA), synthesized by interstitial fibroblasts of various tissues in the body, is taken up and decomposed by the endothelial cells of the liver, and a small amount of small molecules are excreted by glomerular filtration. When the liver and kidney dysfunction, serum HA increased, and with the severity of the disease, HA is a more sensitive indicator of liver function, the diagnosis of early liver cirrhosis is of great significance. In this paper, 67 patients with liver disease serum HA levels were detected by radioimmunoassay; at the same time with the level of AFP (AFP) level analysis to determine its diagnostic value of liver disease, the results are reported as follows: