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目的探讨布洛芬不同给药途径治疗小儿发热的临床疗效。方法将我院2012年12月—2013年3月收治的100例发热患儿分为观察组和对照组,二组均采用布洛芬治疗,对照组口服布洛芬悬浊液,观察组直肠灌入布洛芬悬浊液,比较二组患儿的治疗效果及在用药2,4,6,8h时的腋下体温。结果观察组显效41例,有效6例,总有效率为94.0%;对照组显效40例,有效6例,总有效率为92.0%。二组的总有效率比较差异无统计学意义(P>0.05)。观察组用药4,6,8h时观察组患儿的体温均显著低于对照组(P<0.05)。结论布洛芬治疗小儿发热疗效较好,可根据具体情况选择给药方式,直肠给药降温持续时间长,且无明显副作用,值得推广。
Objective To investigate the clinical efficacy of different routes of administration of ibuprofen in children with fever. Methods 100 cases of fever in our hospital from December 2012 to March 2013 were divided into observation group and control group, the two groups were treated with ibuprofen, the control group oral ibuprofen suspension, observation group rectal The ibuprofen suspension was infused to compare the therapeutic effect of the two groups of children and the axillary body temperature at the time of treatment of 2,4,6,8h. Results In the observation group, 41 cases were markedly effective and 6 cases were effective. The total effective rate was 94.0%. In the control group, 40 cases were markedly effective and 6 cases were effective. The total effective rate was 92.0%. There was no significant difference in the total effective rate between the two groups (P> 0.05). The body temperature in observation group was significantly lower than that in control group at 4, 6, and 8 h (P <0.05). Conclusion Ibuprofen is effective in treating children with fever and can be administered according to the specific conditions. Rectal administration has a long duration of cooling and no obvious side effects, which is worthy of promotion.