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目的探讨丙泊酚联合氯诺昔康(可寒风)在无痛人工流产术的麻醉效果。方法选择ASAⅠ~Ⅱ级无痛人工流产患者100例,随机分成2组,每组50例,Ⅰ组静注芬太尼1μg/kg,Ⅱ组静注氯诺昔康0.15 mg/kg。然后2组患者静注丙泊酚2 mg/kg,注药时间30 s,待患者入睡后开始手术。术中视患者的反应每次追加丙泊酚30~50 mg至手术结束。观察SBP、DBP、HR和SpO2变化,观察两组患者的镇痛情况,术后宫缩情况,记录丙泊酚的总量,清醒时间,清醒后离院时间。结果2组患者术中安静,镇痛效果好,术后宫缩痛轻,用药后SBP、DBP、HR和SpO2均呈一过性下降(P<0.05),但均在正常范围内,术毕清醒较快,两组清醒速度和清醒后离院时间差异无显著性(P>0.05)。结论丙泊酚联合氯诺昔康用于无痛人工流产可减少丙泊酚用量,麻醉效果好,患者苏醒早,术后宫缩痛轻。
Objective To investigate the anesthetic effect of propofol combined with lornoxicam (cold wind) in painless artificial abortion. Methods A total of 100 ASA Ⅰ ~ Ⅱ painless induced abortion patients were randomly divided into 2 groups (n = 50 in each group). Group Ⅰ received fentanyl 1 μg / kg intravenously and group Ⅱ received lornoxicam 0.15 mg / kg. Then two groups of patients intravenous infusion of propofol 2 mg / kg, injection time 30 s, until the patient fell asleep after surgery. Intraoperative visual response to patients each additional propofol 30 ~ 50 mg to the end of surgery. The changes of SBP, DBP, HR and SpO2 were observed. The analgesic conditions, postoperative contractions, the total amount of propofol, awake time and the time of leaving hospital after awake were observed. Results The patients in the two groups had quiet intraoperative, good analgesic effect and mild postoperative uterine contractions. The SBP, DBP, HR and SpO2 were decreased transiently (P <0.05) after treatment, but all were within the normal range. Awake faster, the two groups awake speed and after leaving the hospital was no significant difference (P> 0.05). Conclusion Propofol combined with lornoxicam for painless induced abortion can reduce the dosage of propofol, anesthesia effect is good, the patients wake up early and postoperative contractions pain.