当前生命科学在研究方法上面临着巨大的技术和理论的挑战 ,即如何从结构、功能和生物学过程调控的角度解释一个物种基因序列中所含的信息。这个问题的关键是研判一个未知基因的功能与其他基因产物及其亚细胞结构之间的功能联系 ,不能只通过对核酸一级结构的检测来确定。现就在上述背景下快速发展的蛋白质组学研究中的一些问题作一简要概述 Current life sciences face enormous technological and theoretical challenges in research methods, namely how to interpret the information contained in a species’s gene sequence from the perspective of structural, functional and biological process control. The crux of the problem is to determine the functional relationship between the function of an unknown gene and other gene products and their subcellular structures, which can not be determined only by the detection of the primary structure of the nucleic acid. A brief overview of some of the problems in proteomics that are rapidly evolving under these circumstances