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目的:分析复发性尿路感染患者细菌的分布及其抗感染治疗的疗效。方法:选取2014年1月—2015年5月期间收治的复发性尿路感染患者86例临床资料,按尿液细菌培养与药敏试验结果,合理选用或调整抗菌药物治疗,分析抗菌药物治疗后的临床疗效和复发情况。结果:86例复发性尿路感染患者中,经尿液标本细菌培养结果示阳性者34例,其阳性率为39.53%,其中大肠埃希菌所占61.76%;经药敏试验结果示大肠埃希菌对亚胺培南、第3代头孢菌素和氟喹诺酮类抗菌药物较敏感,而对氨苄西林、阿莫西林-克拉维酸的耐药性较高;治疗后的总有效率为97.40%;其中7例患者用药疗程为3月的复发率为22.58%,经随访2年,复发者11例总复发率为14.28%。结论:复发性尿路感染患者抗感染治疗,应根据其药敏试验结果合理选用抗菌药物,并确保治疗时间在3~6月内,以保证其发挥最大疗效。
Objective: To analyze the distribution of bacteria in patients with recurrent urinary tract infection and the efficacy of anti-infective therapy. Methods: From January 2014 to May 2015, 86 patients with recurrent urinary tract infection were enrolled in this study. According to the results of bacterial culture and susceptibility test in urine, rational use or adjustment of antimicrobial agents was conducted. After antimicrobial treatment The clinical efficacy and recurrence. Results: Of the 86 patients with recurrent urinary tract infection, 34 cases were positive by bacterial culture in urine samples, the positive rate was 39.53%, of which 61.76% were Escherichia coli. The result of drug susceptibility test showed that large intestine Cimicifuga sensitive to imipenem, third generation cephalosporins and fluoroquinolones antibiotics more sensitive to ampicillin, amoxicillin - clavulanic acid resistance; after treatment, the total effective rate was 97.40 %. The recurrence rate of 7 patients in March was 22.58%. After a follow-up of 2 years, the recurrence rate was 14.28% in 11 cases. Conclusion: The anti-infective treatment of patients with recurrent urinary tract infection should be based on the results of its susceptibility testing rational use of antimicrobial agents, and to ensure that the treatment time in 3 to 6 months to ensure its maximum efficacy.