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目的:探讨胶质瘤手术术后瘤内植入125Ⅰ粒子短程放疗的疗效。方法:选取18例脑胶质瘤患者手术术后瘤内植入125Ⅰ粒子作治疗组,并选取19例胶质瘤手术后不加瘤内放疗的患者作对照,观察两组肿瘤复发时间、生存时间、2年生存率和3 年生存率。结果:治疗组与对照组复发时间及生存时间比较,复发时间明显延长,生存时间增加(P<0.01,P<0.05);治疗组与对照组2年生存率和3年生存率比较均明显提高(P<0.05,P<0.05)。结论:胶质瘤患者术后予125Ⅰ粒子瘤内放疗,可提高患者生存时间。有效地缓解病情,提高病人的生存质量,延长患者的生命。
Objective: To investigate the curative effect of 125I seeds short-term radiotherapy after glioma surgery. Methods: Eighteen cases of glioma were enrolled in this study. 125 I seeds were implanted into the tumor-bearing group. Nineteen patients with glioma who did not receive intratumoral radiotherapy were selected as controls. The tumor recurrence time, survival time Time, 2-year survival and 3-year survival. Results: Compared with the control group, the recurrence time and survival time of the treatment group and the control group were significantly prolonged and the survival time was increased (P <0.01, P <0.05). The 2-year survival rate and 3-year survival rate of the treatment group and the control group were significantly increased (P <0.05, P <0.05). Conclusion: Glioma in patients with intracavitary 125I radiotherapy, can improve the survival time of patients. Effectively alleviate the condition, improve the quality of life of patients and prolong the life of patients.