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5. Metformin regulates inflammation and fibrosis in diabetic kidney disease through TNC/TLR4/NF-κB/miR-

Metformin regulates inflammation and fibrosis in diabetic kidney disease through TNC/TLR4/NF-κB/miR-

来源 :世界糖尿病杂志:英文版(电子版) | 被引量 : 0次 | 上传用户：woaibaobei123321

【摘 要】

：

BACKGROUND Type 2 diabetes mellitus(T2DM)is significantly increasing worldwide,and the incidence of its complications is also on the rise.One of the main compli

【作 者】

：

Yang Zhou Xiao-Yu Ma Jin-Yu Ha 

【机 构】

：

DepartmentofEndocrinology,DepartmentofGerontology,DepartmentofClinicalLaboratory,DepartmentofEndocri

【出 处】

：

世界糖尿病杂志:英文版(电子版)

【发表日期】

：

2021年1期

【关键词】

：

TENASCIN-C miR-155-5p METFORMIN Type 2 diabetes mellitus Diabetic kidney disease 

【基金项目】

：

Supported by National Key Research and Development Program of China,No.2018YFC1313900 and No.2018YFC1313901,The Higher School High-end Talent Team Construction of Liaoning Province,No.[2014]187.

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BACKGROUND Type 2 diabetes mellitus(T2DM)is significantly increasing worldwide,and the incidence of its complications is also on the rise.One of the main complications of T2DM is diabetic kidney disease(DKD).The glomerular filtration rate(GFR)and urinary

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