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目的:探究硫酸镁联合硝苯地平治疗对妊高征的临床应用价值。方法:选取本院自2011年5月至2015年5月间进行治疗的妊高征患者52例,随机将其分成对照组和研究组,前者26例,采用硫酸镁单独治疗,后者26例,采用硫酸镁、硝苯地平联合治疗,然后对比观察两组患者治疗前后血压、相关临床指标变化以及妊娠结局。结果:结果显示,经过各自的治疗后,研究组患者的各项临床指标改善情况明显优于对照组,其临床总有效率高于对照组,收缩压和舒张压、24h尿蛋白定量、血细胞比容、血粘度以及RI和S/D均明显低于对照组,比较差异具有显著性,(P<0.05)具有统计学意义。此外,研究组产后出血、早产、胎盘早剥以及剖宫产的发生率明显低于对照组,比较具有显著性差异,(P<0.05)具有统计学意义。结论:对妊高征患者实施硫酸镁联合硝苯地平治疗,不仅能够有效改善患者的临床指标,还有利于产妇正常妊娠,并且并发症较少。
Objective: To investigate the clinical value of magnesium sulfate combined with nifedipine in the treatment of pregnancy-induced hypertension. Methods: Fifty-two PIH patients treated in our hospital from May 2011 to May 2015 were randomly divided into control group and study group. The former was treated with magnesium sulfate alone and the latter 26 patients , Using magnesium sulfate, nifedipine combined treatment, and then compared the two groups of patients before and after treatment of blood pressure, changes in relevant clinical indicators and pregnancy outcomes. Results: The results showed that after the respective treatment, the study group patients improved significantly all the clinical indicators than the control group, the total effective rate was higher than the control group, systolic and diastolic blood pressure, 24h urinary protein, hematocrit Volume, blood viscosity and RI and S / D were significantly lower than the control group, the difference was significant (P <0.05) with statistical significance. In addition, the incidence of postpartum hemorrhage, premature labor, placental abruption and cesarean section in the study group was significantly lower than that in the control group, with significant difference (P <0.05). Conclusion: The treatment of patients with PIH with magnesium sulfate combined with nifedipine not only can effectively improve the clinical indicators of patients, but also conducive to normal maternal pregnancy, and fewer complications.