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作者报道1例重度糖尿病性微血管病患者具正常葡萄糖耐量,尸检证实垂体前叶梗塞。患者女,44岁,因腰部浅表脓肿检查而发现糖尿病。血糖317mg/dl,尿糖阳性,重度蛋白尿,肌酐清除率为52ml/min/1.73m~2。控制饮食后血糖迅速降至正常。半年后,因视力模糊检查发现双眼患重度增殖性视网膜病。尿蛋白高达2.5g/24h,肾小球滤过率为51ml/min/1.73m~2。左肾活检证实为糖尿病性肾小球硬化。多次血糖测定均在正常范围。葡萄糖耐量试验亦正常。甲状腺及肾上腺皮质功能均正常,血浆生长
The authors report that one patient with severe diabetic microangiopathy had normal glucose tolerance and an autopsy confirmed anterior pituitary infarction. Female patient, 44 years old, diagnosed with diabetes due to superficial abscess of the waist. Blood sugar 317mg / dl, urine positive, severe proteinuria, creatinine clearance rate of 52ml / min / 1.73m ~ 2. After the control of blood glucose quickly dropped to normal. Six months later, due to blurred vision examination found that eyes suffering from severe proliferative retinopathy. Urinary protein up to 2.5g / 24h, glomerular filtration rate of 51ml / min / 1.73m ~ 2. Left renal biopsy confirmed diabetic glomerulosclerosis. Multiple blood glucose measurements are in the normal range. Glucose tolerance test is normal. Thyroid and adrenal function are normal, plasma growth