目的对肺癌高危人群的痰液基脱落细胞进行筛查,探讨其在肺癌筛查及早期诊断中的作用。方法本文应用痰液基细胞学联合多排螺旋CT对70例肺癌高危患者进行检查。结果检出6例周围型肺癌,其中1例为早期亚段支气管肺癌,检出率为10.0%。结论联合二项技术筛查的初步结果显示可以提高早期肺癌的检出率,不失为肺癌早期筛查的一种敏感方法。 Objective To screen sputum-based exfoliated cells in high-risk lung cancer patients and explore their roles in screening and early diagnosis of lung cancer. Methods In this paper, sputum-based cytology combined with multi-slice spiral CT in 70 patients with high-risk lung cancer were examined. Results Six cases of peripheral lung cancer were detected, of which one was early sub-stage bronchogenic carcinoma with a detection rate of 10.0%. Conclusions The preliminary results of combined two technical screening show that it can improve the detection rate of early lung cancer, which is a sensitive method for early screening of lung cancer.