肠道病毒持续感染是扩张型心肌病(dilated cardiomyopathy,DCM)发生的重要病因,然而病毒感染后导致DCM发生的机制至今尚不明了。研究表明:肠道病毒一方面可以在心肌组织中持续复制,进而通过自身蛋白酶直接损伤心肌细胞,或是通过机体的免疫系统对心肌产生间接的损伤;另一方面,病毒也可以一种自然变异的形式在心肌中长期潜伏。 Continuous infection with enteroviruses is an important cause of dilated cardiomyopathy (DCM). However, the mechanism of DCM infection after infection is still unknown. Studies have shown that: on the one hand, enterovirus can continue to replicate in myocardial tissue, and then directly through their own protease damage to myocardial cells, or indirectly through the body’s immune system myocardial injury; the other hand, the virus can also be a natural mutation The form of long-term latent in the myocardium.