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本文共选择在外院经1次以上治疗后又转移复发的恶性黑色瘤41例。全组中位生存时间20.2个月,2年生存率53.6%,5年生存率4.8%。手术结合瘤苗治疗27例,单纯手术治疗14例,前者中位生存时间明显长于后者,34.3个月和17.5个月(P=0.0001)。全组完全数据33例,截尾数据8例(80.48%,19.5%)。肿瘤患者的年龄、性别、大小及肿瘤部位在2组中的分布无差别(P=0.99,P=0.19,P=0.57)。在生存分布上下列诸因素间无差异:年龄P=0.43,性别P=0.4,部位P=0.72。结果分析显示恶性黑色素瘤患者生存时间与肿瘤的大小及是否使用瘤苗有关。
In this study, 41 cases of metastatic malignant tumors that had undergone metastasis and recurrence after treatment in the external hospital were selected. The overall median survival time was 20.2 months, the 2-year survival rate was 53.6%, and the 5-year survival rate was 4.8%. Twenty-seven patients underwent surgery combined with tumor vaccines and 14 underwent surgery alone. The median survival time of the former was significantly longer than that of the latter, 34.3 months and 17.5 months (P=0.0001). There were 33 cases of complete data in the whole group and 8 cases of censored data (80.48%, 19.5%). There was no difference in the distribution of age, gender, size, and location of tumors among the two groups (P = 0.99, P = 0.19, P = 0.57). There were no differences among the following factors in survival distribution: age P=0.43, gender P=0.4, and site P=0.72. Analysis of the results showed that the survival time of malignant melanoma patients was related to the size of the tumor and whether or not it was used.