新生儿由于非特异性和特异性免疫功能缺陷,易致感染,新生儿期感染性疾病的发生率较生命的任何阶段均高,且易发展成败血症,危及生命。近年国外新生儿败血症的发生率占全部活产婴的1～4‰,病死率高达17～45%。国内新生儿败血症的发生率和病死率依不同医院而异。熟悉新生儿围生期细菌感染的临床特点,对指导预防、诊断和治疗具有重要意义。 Neonatal due to non-specific and specific immune dysfunction, easy to cause infection, the incidence of infectious diseases in the neonatal period than any stage of life are high, and easy to develop into sepsis, life-threatening. In recent years, the incidence of neonatal sepsis in foreign countries accounted for 1 to 4 ‰ of all live births, with a mortality rate of 17-45%. Domestic neonatal sepsis incidence and mortality varies according to different hospitals. Familiar with the clinical features of neonatal perinatal bacterial infection, to guide the prevention, diagnosis and treatment of great significance.