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目的：验证复方右美沙芬颗粒剂镇咳、祛痰及改善鼻塞的疗效。方法：对１２０例咳嗽、咳痰或伴有鼻塞的呼吸道疾病病人，采用双盲双模拟分层随机对照法分为复方右美沙芬颗粒剂组和美愈伪麻胶囊组。结果：复方右美沙芬颗粒剂组镇咳及祛痰总有效率为８５％，美愈伪麻胶囊组为７５％，组间经Ｒｉｄｉｔ检验，差别无显著意义（Ｐ＞０．０５）。复方右美沙芬颗粒剂组与美愈伪麻胶囊组镇咳及祛痰的起效时间为２５ｈ±２２ｈ，２３ｈ±１６ｈ；２８ｈ±２３ｈ，２５ｈ±１８ｈ，显效时间为３．１ｈ±１．２ｈ，３．１ｈ±１．４ｈ；３．６ｈ±１．１ｈ，３．４ｈ±１．１ｈ。２组比较差别无显著意义。２组鼻塞改善显著，不良反应轻微。结论：复方右美沙芬颗粒剂具有明显的镇咳、祛痰及改善鼻塞的疗效，不良反应少
Objective: To verify the efficacy of compound dextromethorphan granules in antitussive, expectorant and nasal congestion improvement. Methods: One hundred and twenty patients with respiratory diseases with cough, sputum, or nasal congestion were divided into two groups: double-blind and double-simulated stratified randomized controlled trials. The patients were divided into two groups: compound dextromethorphan granules group and Meiyu pseudoephedrine capsule group. Results: The total effective rate of antitussive and sputum was 85% in compound dextromethorphan granule group, and 75% in Meiyu pseudoephedrine capsule group. There was no significant difference between the two groups after Ridit test (P>0.05). The onset time of antitussive and expectorant in compound dextromethorphan granules group and Meiyu pseudoephedrine capsule group was 25h±22h, 23h±16h, 28h±23h, 25h±18h, and the effective time was 3.1h±1.2h. , 3.1 h ± 1.4 h; 3.6 h ± 1.1 h, 3.4 h ± 1.1 h. There was no significant difference between the two groups. The nasal congestion improved significantly in both groups, and the adverse reactions were mild. Conclusion: Compound dextromethorphan granules have obvious antitussive, expectorant and nasal congestion effects, with fewer adverse reactions.