Dilevalol是拉贝洛尔(labetalol)的R-R光学异构体,为β_1和β_2受体竞争性拮抗剂,强效选择性β_2受体激动剂,本品通过β_2受体介导血管扩张作用,从而使外周血管阻力下降,临床证明对高血压病有效。作者研究了静注Dilevalol对重度高血压的效果。 12例重度高血压患者(卧位舒张压124±2mmHg),缓慢静注Dilevalol,起始量25mg,以后依次25、50和100mg,每隔20分钟1剂,其中100mg剂量连续5次,总量600 mg。治疗目标是使卧位舒张压< Dilevalol, an RR optical isomer of labetalol, is a competitive antagonist of beta 1 and beta 2 receptors and a potent and selective beta 2 receptor agonist. This product mediates vasodilation via beta 2 receptors and thus Peripheral vascular resistance decreased, clinically proven effective on hypertension. The authors studied the effect of intravenous Dilevalol on severe hypertension. 12 patients with severe hypertension (supine diastolic pressure 124 ± 2mmHg), intravenous Dilevalol, the initial amount of 25mg, followed by 25,50 and 100mg, every 20 minutes one dose, of which 100mg dose for 5 consecutive times, the total 600 mg. Treatment goal is to make supine diastolic pressure <