血管内皮生长因子 (ＶＥＧＦ)为高度特异的血管内皮细胞促有丝分裂素 ,可直接导致肿瘤血管的形成[1-3 ] 。我们利用免疫组化技术检测ＶＥＧＦ在膀胱癌中的表达 ,以探讨其与膀胱癌浸润、复发的关系。1　材料与方法1.1.　临床资料　收集 1996— 2 0 0 1年间的膀胱癌患者的石蜡包 Vascular endothelial growth factor (VEGF) is a highly specific vascular endothelial cell mitogen, can lead directly to the formation of tumor blood vessels [1-3]. We use immunohistochemistry to detect the expression of VEGF in bladder cancer to explore its relationship with bladder cancer invasion and recurrence. 1 Materials and Methods 1.1 Clinical data collected from 1996 to 2001 paraffin package of bladder cancer patients