探讨阿托伐他汀治疗急性ST段抬高型心肌梗死合并高血压的效果观察

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目的:探讨阿托伐他汀治疗急性ST段抬高型心肌梗死合并高血压患者的临床效果.方法:2016年12月~2017年1月我院收治的82例急性ST段抬高型心肌梗死合并高血压患者,随机分为对照组和观察组,每组41例,对照组口服依那普利及氯沙坦钾片,观察组在对照组基础上加用阿托伐他汀,对比两组治疗前后效果分析.结果:观察组显效13例高于对照组5例(P<0.05).治疗后观察组LVPW、LVEDD、LVEF和LVESD优于对照组,存在统计学意义(P<0.05).观察组TC、LDL-C及CRP低于对照组,观察组HDL-C高于对照组,存在统计学意义(P<0.05);观察组SBP和Lp-PLA2低于对照组,观察组CO和CI高于对照组,存在统计学意义(P<0.05).结论:阿托伐他汀能降低高血压并发ST段抬高型心肌梗死患者的血压及Lp-PLA2水平,改善脂代谢,能延缓心肌梗死后的心室重构进程,提高患者心脏功能.
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