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Vascular smooth muscle cell(SMC)differentiation is an important process in vasculogenesis and angiogenesis during embryonic development.The alterations in the differentiated state in SMCs contribute to a variety of major cardiovascular diseases such as atherosclerosis,hypertension,restenosis and vascular aneurysm~([1-2]).A better understanding of the cellular and molecular mechanisms that control SMC differentiation is essential to help develop new approaches to
Vascular smooth muscle cell (SMC) differentiation is an important process in vasculogenesis and angiogenesis during embryonic development. The alterations in the differentiated state in SMCs contribute to a variety of major cardiovascular diseases such as atherosclerosis, hypertension, restenosis and vascular aneurysm ~ ([1 -2]). A better understanding of the cellular and molecular mechanisms that control SMC differentiation is essential to help develop new approaches to