自1896年Van Ermengern在比利时的一次音乐会中,因进食生火腿引起食物中毒的标本中分离到肉毒梭状杆菌(简称肉毒杆菌),并指出该菌在合适环境中产生的外毒素与疾病直接有关后,距今已80余年。肉毒中毒历年来国内外文献中均有报导,如美国从1899～1974年共暴发了708起肉毒中毒,发病人数计1814人,平均每年24.2例。国内早在50年代就有肉毒中毒的报告,60年代亦有多起肉毒中毒发生,最近也有较大系列 Since a concert by Van Ermengern in Belgium in 1896, Clostridium botulinum (Clostridium botulinum) has been isolated from samples of food poisoning caused by eating raw ham and pointed out that the exotoxin produced by this bacterium in a suitable environment is associated with After the disease is directly related, more than 80 years ago. Botulism has been reported in the literature both at home and abroad over the years. For example, a total of 708 botulism cases were reported in the United States from 1899 to 1974, with an incidence of 1814, averaging 24.2 cases per year. There was a report of botulism in China in the 1950s. In the 1960s, there were also many cases of botulism and recently there was a larger series