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恶性胸膜间皮瘤几乎是暴露于石棉的必然结果,只不过发病的时间滞后,很少低于25年,从第一次接触石棉到发病一般都在50年以上。20世纪40年代,每100个出生的人中就有一个将死于此病。其中半数病例现已年过70,80%是男性。对于一个青少年时就接触石棉,现在仍处于高危行业(比如绝缘业)的男性来说,在他工作的一生中发生间皮瘤的危险高到每5个人中会有1个人发病。目前在英格兰每年有1800例以上死亡病例(大约每200例死亡男性和每1500例死亡女性中有1例死于本病),而且这个数字还在上升。由于石棉暴露在英国一直持续至1980年,估计流行高峰即将来临,因此我们需要研究这些病人的处理方法。
Malignant pleural mesothelioma is almost an inevitable result of exposure to asbestos, but the incidence of lag time, rarely less than 25 years, from the first exposure to asbestos to the incidence are generally more than 50 years. In the 1940s, one out of every 100 people died of the disease. Half of these cases are now over 70, 80% male. For a man who is exposed to asbestos in adolescence and is still in high-risk industries (such as insulation), the risk of mesothelioma in his lifetime is as high as 1 out of every 5 people. There are currently over 1,800 deaths (approximately every 200 deaths and 1 in 1500 deaths) in England each year, and this figure is still on the rise. As the exposure of asbestos in the UK continued until 1980, it is estimated that the peak of the epidemic is approaching, so we need to study the treatment of these patients.