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目的探讨精神分裂症患者人格特征及其与儿童期虐待的相关性。方法应用三维人格问卷(tridimensional personality questionnaire,TPQ)及儿童期虐待问卷(childhood trauma questionnaire-short form,CTQ-SF)对210例精神分裂症患者(病例组)及190例正常人(对照组)进行测评。结果病例组TPQ评分在伤害回避维度高于对照组,在奖赏依赖维度低于对照组(P<0.01);单因素分析发现,病例组寻求刺激维度与情感虐待、性虐待及CTQ-SF总分显著相关,伤害回避维度与躯体忽视显著相关,奖赏依赖维度与性虐待及CTQ-SF总分显著相关。多元逐步回归分析发现,情感虐待是寻求刺激维度的最佳预测因素,CTQ-SF总分是奖赏依赖维度的最佳预测因素。结论精神分裂症患者在TPQ伤害回避维度及奖赏依赖维度具有独特的特征,儿童期虐待对其人格特征可能具有一定影响。
Objective To investigate the personality traits of schizophrenia patients and their correlation with childhood abuse. Methods Totally 210 schizophrenia patients (case group) and 190 normal controls (control group) were enrolled in this study. The tridimensional personality questionnaire (TPQ) and childhood trauma questionnaire-short form (CTQ-SF) Evaluation. Results In the case group, the TPQ score was higher in the injury avoidance dimension than in the control group, and the reliance dimension was lower than that in the control group (P <0.01). The univariate analysis showed that the case group sought stimulation dimension and emotional abuse, sexual abuse and CTQ-SF score Significantly, the dimension of injury avoidance was significantly associated with physical neglect, and the dimension of reward dependence was significantly associated with sexual abuse and CTQ-SF scores. Multivariate stepwise regression analysis found that emotional abuse was the best predictor of the stimulus dimension, and the CTQ-SF total score was the best predictor of the reward-dependent dimension. Conclusions Patients with schizophrenia have unique characteristics of avoidance dimension and reward-dependent dimension in TPQ. Childhood abuse may have some impact on their personality traits.