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目的观察初发 GD 患者甲状腺自身抗体情况及其影响因素。方法选取我院2012~2014年内分泌科、核医学科门诊就诊的1935例临床确诊初发 GD 患者，检测甲状腺功能、甲状腺相关抗体的滴度水平。分析在初发 GD 患者中甲状腺功能对 GD 的影响。结果 FT3、FT4、TPOAb、TGAb 对 TRAb 的影响有统计学意义(<0.05)，且均为正向影响；FT3、FT4、TRAb、TGAb 对 TPOAb 的影响有统计学意义(<0.05)，且均为正向影响；FT3、FT4、TPOAb、TRAb 对 TGAb 的影响有统计学意义(<0.05)，且均为正向影响。结论在初发 GD 患者中，甲状腺功能、甲状腺自身抗体之间是相互影响的。“,”Objective To observation of thyroid autoantibodies in patients with incipient GD and its influencing factors.Methods Choose from 2012-2014 of 1935 cases of endocrinology, nuclear medicine clinics clinical diagnosis of incipient GD patients, testing thyroid function, thyroid antibody drop degree level.Analysis of thyroid function in patients with incipient GD influence of GD.Results The FT3, FT4, TPOAb, TGAb affect TRAb was statistically significant ( < 0.05), and all is positive influence;FT3, FT4, TRAb, TGAb affect TPOAb was statistically significant ( < 0.05), and all is positive influence;FT3, FT4, TPOAb, TRAb affect TGAb was statistically significant ( < 0.05), and all is positive influence.Conclusion In patients with incipient GD, thyroid function, thyroid autoantibodies is influence each other.