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本文对９７例尖锐湿疣（ＣＡ）进行聚合酶链反应检测人乳头瘤病毒（ＨＰＶ）ＤＮＡ及光镜下观察凹空细胞的特征。结果显示，９５例有凹空细胞，占９７．９４％。凹空细胞多分布在棘层的中、上层。根据核的改变将凹空细胞分为九型，以镰刀形核、毛虫样核和核大浓染型出现例数最多，分别为７５／９５、７４／９５和６１／９５，此三型对ＣＡ最有诊断价值。ＨＰＶ６、１１阳性９３例（９５．８８％），ＨＰＶ１６、１８、３１、３３、５２ｂ、５８阳性２例（２．０６％），ＨＰＶ６、１１、１６、１８、３１、３３、５２ｂ、５８阴性２例（２．０６％），但有典型的凹空细胞。２例ＣＡ无凹空细胞而ＨＰＶ６、１１为阳性。
In this paper, 97 cases of genital warts (CA) were detected by polymerase chain reaction of human papillomavirus (HPV) DNA and observed the characteristics of concave cells under light microscope. The results showed that 95 cases with concave cells, accounting for 97.94%. Concave cells are distributed in the stratum spinosum, the upper. According to the change of nucleus, the empty cells were divided into nine types, with the largest number of sickle-shaped nucleus, caterpillar-like nucleus and large nuclear staining, accounting for 75/95, 74/95 and 61/95, respectively The most diagnostic value of CA. HPV6, 11 positive 93 cases (95.88%), HPV16,18,31,33,52b, 58 positive in 2 cases (2.06%), HPV6,11,16,18,31,33,52 b, 58 negative 2 cases (2.06%), but there are typical concave cells. Two cases of CA without concave cells and HPV6, 11 were positive.