免疫记忆细胞在生成之后发生自稳性增殖以维持机体免疫记忆,这个过程发生在何处一直是免疫学研究的一个关注点。记忆性CD8和B细胞在生成后定位在骨髓中,依赖于周围环境中的生长因子存活和增殖。传统观念认为,记忆性CD4+细胞生成后一直在外周循环,以便能在第一时间发现外周可能 Immune memory cells in the generation of self-stable proliferation to maintain the body’s immune memory, the occurrence of this process has been a focus of immunological research. Memory CD8 and B cells are localized in the bone marrow after their production and depend on the survival and proliferation of growth factors in the surrounding environment. The traditional view is that memory CD4 + cells have been peripheral circulation in the generation so that the peripheral can be found in the first time