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目的:探讨HIV感染相关性宫颈癌的发病率和一般临床特点。方法:收集2008年4月~2012年3月间住院治疗的全部HIV阳性宫颈癌患者(A组)的临床资料,同时收集2010年3月间连续入院同等数量HIV阴性宫颈癌患者(B组)的临床资料,将两组资料进行对比。结果:两组患者在发病年龄(P=0.038)、T淋巴细胞亚群构成(P=0.000)及全身多发淋巴结肿大发生率(P=0.003)方面均有统计学差异。结论:HIV阳性宫颈癌患者较HIV阴性患者发病更早、T淋巴细胞免疫功能下降、全身多发淋巴结肿大发生率显著增加,提示HIV感染导致免疫功能低下,在HIV阳性宫颈癌发生过程中发挥了重要作用。
Objective: To investigate the incidence of HIV-related cervical cancer and its clinical features. Methods: The clinical data of all HIV-positive cervical cancer patients (A group) hospitalized from April 2008 to March 2012 were collected. At the same time, patients with the same number of HIV-negative cervical cancer (group B) The clinical data, the two groups of data for comparison. Results: There was a significant difference between the two groups in age of onset (P = 0.038), T lymphocyte subsets formation (P = 0.000) and the incidence of systemic multiple lymphadenopathy (P = 0.003). Conclusion: The incidence of HIV-positive cervical cancer patients is earlier than that of HIV-negative patients, the immune function of T lymphocytes is decreased and the incidence of systemic multiple lymphadenopathy is significantly increased, suggesting that HIV infection can lead to low immunocompetence and play a role in the development of HIV-positive cervical cancer Important role.