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对郑州市金水区内1~5岁的流动儿童及同龄常住儿童的脊髓灰质炎(脊灰)免疫状况及抗体水平,进行随机抽查并分别做了分析评价.流动儿童中达到>3次服苗的占80%,常住儿童占98%。采用脊灰中和抗体测定法测定流动儿童脊灰中和抗体,脊灰Ⅰ、Ⅱ、Ⅲ型抗体阳性率分别为96%、98%、94%;3个型抗体几何平均滴度(GMT)分别为Ⅰ型1:110,Ⅱ型1:202,Ⅲ型1:的常住儿脊灰中和抗体阳性率Ⅰ、Ⅱ、Ⅲ型均为100%,3个型抗体GMT分别为Ⅰ型1:298、Ⅱ型1:377、Ⅲ型1:229.结果提示两组儿童的抗体水平有差别。如何提高流动儿童的免疫接种率,是当今计划免疫工作所面临的一大难题.通过本次调查分析,为今后加强流动儿童的计划免疫管理提供了一定的依据。
Polio (poliomyelitis) immune status and antibody levels of migrant children and children of the same age who lived in Jinshui District of Zhengzhou City were randomly selected and analyzed respectively. Of the floating children, 80% of the patients received> 3 servings of vaccine and 98% of the resident children. The positive rates of poliovirus types Ⅰ, Ⅱ and Ⅲ were 96%, 98% and 94%, respectively. The mean geometric mean titers (GMTs) The positive rates of neutralizing antibodies in poliovirus of type Ⅰ, Ⅱ and Ⅲ were 100% for type Ⅰ 1: 110, type Ⅱ 1: 202 and type Ⅲ 1: respectively. The three types of antibodies GMT were type Ⅰ 1: 298, Type II 1: 377, Type III 1: 229. The results suggest that there is a difference between the two groups of children’s antibody levels. How to raise the vaccination rate of migrant children is a major challenge in today’s planned immunization work. Through this survey and analysis, it provides some evidences for strengthening the immunization management of migrant children in the future.