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晚期肺癌疗效甚差，其综合治疗仍是目前临床研究的重点，对17例失去手术机会的晚期肺癌进行支气管动脉灌注化疗（BAI）和肿瘤体内局部免疫治疗即双介入治疗（A组），并与同期肺癌10例单纯肿瘤体内局部免疫治疗（B组）、16例单纯BAI治疗（C组）、18例传统化疗（D组）比较疗效，A组完全缓解（CR）2例，部分缓解（PR）13例，近期有效率CR＋PR83．33％，明显优于B组CR＋PR50．00％、C组CR＋PR56．25％和D组CR＋PR33．33％，有统计学意义。A组6例重获Ⅱ期手术适应证，2例手术切除术后病理显示癌细胞大片变性、坏死。单纯局部免疫治疗方法简单，近期疗效接近C、D两组，毒副作用少。双介入治疗晚期肺癌具有较大的应用价值，为晚期肺癌提供了新的有效、简便的治疗方法。
The efficacy of advanced lung cancer is very poor, and its comprehensive treatment is still the focus of current clinical research. Bronchial arterial infusion chemotherapy (BAI) and intratumoral local immunotherapy (double interventional therapy) (A group) are performed on 17 patients with advanced lung cancer who have lost surgery. Compared with 10 lung cancer patients treated with local immunotherapy (group B), 16 patients with BAI alone (group C), and 18 patients with traditional chemotherapy (group D), there were 2 cases of complete remission (CR) and partial remission in group A. PR) 13 cases, the recent effective CR + PR 83.33%, significantly better than CR + PR 50.00% in group B, CR + PR 56.25% in group C and CR + PR 33.33% in group D, with statistical significance. In group A, 6 patients regained indications of stage II surgery, and 2 cases showed pathological degeneration and necrosis of cancer cells after surgical resection. The simple local immunotherapy method is simple, the short-term efficacy is close to C, D two groups, with fewer side effects. Double interventional treatment of advanced lung cancer has great application value and provides a new effective and simple treatment method for advanced lung cancer.