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目的某院临床药师于2015年开始直接参与Ⅰ类切口手术术前讨论,对围手术期抗菌用药提出建议,通过对比药学干预前后抗菌药物的使用情况,观察干预效果。方法采用回顾性方法选择2014年(药学干预前)和2015年(药学干预后)某院骨外科闭合性骨折修复Ⅰ类切口手术各112例,比较干预前后预防用药的比例、用药的时长、药物使用的种类以及药品费用。结果药学干预后预防用药率从83.93%降至20.54%;用药时机术前0.5~2 h控制率为100%;术后用药时长超过24 h从78.57%降至9.82%;病人抗菌药费同比下降57.76%。结论该院Ⅰ类切口手术抗菌药物药学干预措施切实可行,减少病人药费支出的同时降低因滥用或长时间使用抗菌药物产生的细菌耐药性。
Objectives Clinical pharmacists in a hospital started to directly participate in the preoperative study of type Ⅰ incision surgery in 2015 and made suggestions on perioperative antibacterial drug use. By comparing the use of antibacterial drugs before and after the pharmaceutical intervention, the intervention effect was observed. Methods A retrospective study was conducted to select 112 cases of type Ⅰ incision surgery in 2014 (before the intervention) and 2015 (after the intervention) in a hospital. The proportions of prophylaxis before and after intervention, duration of medication, The type of use and the cost of the medicine. Results The rate of prophylaxis was reduced from 83.93% to 20.54% after drug intervention. The time to medication was 100% at 0.5 ~ 2 h before operation, and from 78.57% to 9.82% after operation for 24 hours. 57.76%. Conclusion Class I incision surgical antibacterial drug pharmacological interventions feasible and feasible to reduce the patient’s drug expenditures while reducing the abuse or prolonged use of antibacterial drug-resistant bacteria.