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目的介绍钼靶片引导下立体穿刺定位，美蓝标记加小手术活检方法。方法 １５３例乳腺微小病变患者接受术前钼靶片引导下立体穿刺定位，美蓝标记加手术活检。其中９３例微小钙化，６０例可疑肿块和局部结构紊乱。将标本进行钼靶摄片，确认病灶取下。如病理结果为良性病灶，则随访。如为恶性病灶，则作进一步处理。结果 １５３例中，恶性病灶１１３例（７３．９％），其中浸润性导管癌和小叶癌６２例（４０．５％），原位癌２３例（１５％），粉刺样癌２１例（１３．７％），筛状癌４例（２．７％），粉刺样癌２１例（１３．７％），筛状癌４例（２．７的），微小乳头状癌３例（２％）良性病灶４０例（２６．１％），其中１３例是非典型导管增生。１１２例（７３．２％）手术完全切除，切缘阴性。结论钼靶片引导下立体穿刺定位，美蓝标记乳腺可疑病灶和微小钙化加手术活检方法是一种有效而安全的方法。对于无肿块型可疑病灶，该方法可作为常规检查。
Objective To introduce stereotactic positioning guided by molybdenum target film and methylene blue labeling plus small biopsy. Methods A total of 153 patients with minimal breast lesions received stereotactic guidance under the guidance of preoperative molybdenum target film. The methylene blue labeled with biopsy was used. Ninety-three were microcalcifications, 60 were suspicious masses and local structural disorders. The specimens were taken mammography to confirm the lesion removed. If the pathological result is benign, follow-up. If malignant lesions, then for further processing. Results Of the 153 cases, 113 (73.9%) had malignant lesions, of which 62 (40.5%) had invasive ductal and lobular carcinoma, 23 (15%) had carcinoma in situ and 21 .7%), 4 cases of reticular carcinoma (2.7%), 21 cases of acne-like carcinoma (13.7%), 4 cases of reticular carcinoma (2.7), 3 cases of small papillary carcinoma (2% ) Benign lesions in 40 cases (26.1%), of which 13 cases of atypical ductal hyperplasia. 112 cases (73.2%) were completely surgically removed, and their margins were negative. Conclusion Molybdenum target-guided stereotactic positioning, methylene blue marked suspicious lesions and microcalcification plus surgical biopsy method is an effective and safe method. For lump-like suspicious lesions, the method can be used as a routine examination.