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5. Down-regulation of αGal epitopes by co-transfection of α1,3-galactosidase gene and α1,2-fucosyltrans

Down-regulation of αGal epitopes by co-transfection of α1,3-galactosidase gene and α1,2-fucosyltrans

来源 :中国科学通报：英文版 | 被引量 : 0次 | 上传用户：esshuc

【摘 要】

：

The polycarbohydrate structure of Galα1- 3Galβ1-4GluNAc-R (known as αGal epitopes of xenoantigen), produced by α1-3-galactosyltransferase (α1,3-GT) in the

【作 者】

：

GONG Feng ZHANG Yangpei JIA Ya 

【机 构】

：

BeijingInstituteofTransfusionMedicine

【出 处】

：

中国科学通报：英文版

【发表日期】

：

2005年23期

【关键词】

：

异种移植术 αGal抗原决定基 减量调节 聚多糖 α1-3-半乳糖苷酶 α1-2-墨角藻糖基乳糖 xenotransplantation  αGal epito 

【基金项目】

：

The National Basic Research Program of China，国家高技术研究发展计划(863计划)

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The polycarbohydrate structure of Galα1- 3Galβ1-4GluNAc-R (known as αGal epitopes of xenoantigen), produced by α1-3-galactosyltransferase (α1,3-GT) in the course of animal development, is the major xenoantigen on the cell surface of porcine which causes h

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