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目的 :评价生物胶联合OK-432及博莱霉素治疗颌面部软组织动静脉畸形(arteriovenous malformations,AVMs)的临床疗效。方法:13例颌面部软组织AVMs患者,男8例,女5例,平均年龄28.2岁。在超选择性血管内栓塞基础上,通过经皮注射生物胶联合OK-432及博莱霉素3~5次进行硬化治疗。结果:除术区1周内肿胀外,均无严重并发症出现。随访14~58个月(平均27.4个月),3例治愈,8例显效,2例有效,无无效病例。结论:生物胶联合OK-432及博莱霉素经皮硬化治疗术治疗颌面部软组织AVMs效果良好,方法简单、安全、可靠。
Objective: To evaluate the clinical efficacy of biomaterial combined with OK-432 and bleomycin in the treatment of arteriovenous malformations (maxillofacial AVMs) in maxillofacial region. Methods: Thirteen patients with maxillofacial soft tissue AVMs, 8 males and 5 females, with an average age of 28.2 years. On the basis of superselective endovascular embolization, sclerotherapy is performed by percutaneously injecting bio-gel in combination with OK-432 and bleomycin 3 to 5 times. Results: In addition to swelling within 1 week surgery area, no serious complications occurred. All the patients were followed up for 14-58 months (average 27.4 months), 3 cases were cured, 8 cases markedly effective, 2 cases effective and no ineffective cases. Conclusion: Bio-Glue combined with OK-432 and bleomycin in the treatment of maxillofacial soft tissue AVMs is effective, the method is simple, safe and reliable.